What is the route of administration (R) for paracetamol according to the PICARDS?

The route of administration for paracetamol, as defined in the PICARDS guidelines, is oral. This indicates that paracetamol is primarily designed to be taken by mouth, which allows for effective absorption through the gastrointestinal tract.

Orally administered paracetamol is commonly used due to its convenience and efficacy. Patients can easily self-administer it, allowing for greater accessibility in managing pain and fever. By choosing the oral route, the medication can also be formulated in various forms such as tablets, liquid suspensions, or effervescent powders, catering to a wider range of patient preferences and needs.

In contrast, the other routes listed—intravenous, subcutaneous, and inhalation—are less common for this particular medication and are typically used for different types of medications or in specific clinical scenarios. Each of those methods involves different absorption mechanisms and indications that are not applicable for standard paracetamol treatment.